There's a release of norepinephrine through the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors within the dorsal horn to lessen afferent discomfort transmission and generate analgesia. Consequently, prescription drugs like clonidine that target alpha-2 receptors can influence the transmission of soreness. Extreme Allergic Reactions. Clonidine may possibly ... https://nathaniell957fgn0.techionblog.com/profile