Below, we clearly show that conolidine, a purely natural analgesic alkaloid used in traditional Chinese medication, targets ACKR3, thus giving added evidence of the correlation amongst ACKR3 and ache modulation and opening different therapeutic avenues for the remedy of Long-term soreness. In this case, it enhances the Conolidine’s bioavailability, https://chapliny159upg9.wikiparticularization.com/user